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Applications of Dissolution-DNP for NMR Screening

Experimental screening for protein-ligand interactions is a central task in drug discovery. Nuclear magnetic resonance (NMR) spectroscopy enables the determination of binding affinities, as well as the measurement of structural and dynamic parameters governing the interaction. With traditional liqui...

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Bibliografiske detaljer
Udgivet i:Methods Enzymol
Main Authors: Kim, Yaewon, Hilty, Christian
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8179729/
https://ncbi.nlm.nih.gov/pubmed/30638540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2018.08.016
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