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Applications of Dissolution-DNP for NMR Screening

Experimental screening for protein-ligand interactions is a central task in drug discovery. Nuclear magnetic resonance (NMR) spectroscopy enables the determination of binding affinities, as well as the measurement of structural and dynamic parameters governing the interaction. With traditional liqui...

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Detalhes bibliográficos
Publicado no:Methods Enzymol
Main Authors: Kim, Yaewon, Hilty, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8179729/
https://ncbi.nlm.nih.gov/pubmed/30638540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2018.08.016
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