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Applications of Dissolution-DNP for NMR Screening

Experimental screening for protein-ligand interactions is a central task in drug discovery. Nuclear magnetic resonance (NMR) spectroscopy enables the determination of binding affinities, as well as the measurement of structural and dynamic parameters governing the interaction. With traditional liqui...

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書目詳細資料
發表在:Methods Enzymol
Main Authors: Kim, Yaewon, Hilty, Christian
格式: Artigo
語言:Inglês
出版: 2018
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8179729/
https://ncbi.nlm.nih.gov/pubmed/30638540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2018.08.016
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