Centyrin ligands for extrahepatic delivery of siRNA

RNA interference (RNAi) offers the potential to treat disease at the earliest onset by selectively turning off the expression of target genes, such as intracellular oncogenes that drive cancer growth. However, the development of RNAi therapeutics as anti-cancer drugs has been limited by both a lack...

Full description

Saved in:
Bibliographic Details
Published in:Mol Ther
Main Authors: Klein, Donna, Goldberg, Shalom, Theile, Christopher S., Dambra, Richard, Haskell, Kathleen, Kuhar, Elise, Lin, Tricia, Parmar, Rubina, Manoharan, Muthiah, Richter, Mark, Wu, Meizhen, Mendrola Zarazowski, Jeannine, Jadhav, Vasant, Maier, Martin A., Sepp-Lorenzino, Laura, O’Neil, Karyn, Dudkin, Vadim
Format: Artigo
Language:Inglês
Published: American Society of Gene & Cell Therapy 2021
Subjects:
Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8178446/
https://ncbi.nlm.nih.gov/pubmed/33601052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2021.02.015
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items