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Opposing peripheral fates of tissue-restricted self antigen-specific conventional and regulatory CD4(+) T cells

The development of self antigen-specific T cells is influenced by how the self antigen is expressed. Here, we created a mouse in which a model self antigen is conditionally expressed in different tissue environments. Using peptide:MHCII tetramer-based cell enrichment methods, we examined the develop...

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Podrobná bibliografie
Vydáno v:Eur J Immunol
Hlavní autoři: Zhang, Zimeng, Legoux, Francois P., Vaughan, Spencer W., Moon, James J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8176781/
https://ncbi.nlm.nih.gov/pubmed/31580477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201948180
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