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Cutting Edge: Self-antigen controls the balance between effector and regulatory T cells in peripheral tissues
Immune homeostasis in peripheral tissues is achieved by maintaining a balance between pathogenic effector T cells (Teff) and protective Foxp3(+) regulatory T cells (Treg). Using a mouse model of an inducible tissue-antigen we demonstrate that antigen (Ag) persistence is a major determinant of the re...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3925257/ https://ncbi.nlm.nih.gov/pubmed/24442443 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301777 |
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