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Cutting Edge: Self-antigen controls the balance between effector and regulatory T cells in peripheral tissues

Immune homeostasis in peripheral tissues is achieved by maintaining a balance between pathogenic effector T cells (Teff) and protective Foxp3(+) regulatory T cells (Treg). Using a mouse model of an inducible tissue-antigen we demonstrate that antigen (Ag) persistence is a major determinant of the re...

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Библиографические подробности
Главные авторы: Gratz, Iris K., Rosenblum, Michael D., Maurano, Megan M., Paw, Jonathan S., Truong, Hong-An, Marshak-Rothstein, Ann, Abbas, Abul K.
Формат: Artigo
Язык:Inglês
Опубликовано: 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3925257/
https://ncbi.nlm.nih.gov/pubmed/24442443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301777
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