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Memory regulatory T cells require IL-7 and not IL-2 for their maintenance in peripheral tissues()
Thymic Foxp3-expressing regulatory T cells are activated by peripheral self antigen to increase their suppressive function, and a fraction of these cells survive as memory Tregs (mTregs). Memory Tregs persist in non-lymphoid tissue after cessation of antigen expression and have enhanced capacity to...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3660612/ https://ncbi.nlm.nih.gov/pubmed/23543753 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300212 |
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