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An in vivo IL-7 requirement for peripheral FoxP3(+) regulatory T cell homeostasis

All T cells are dependent on IL-7 for their development and for homeostasis. FoxP3(+) T regulatory cells are unique among T cells in that they are dependent on IL-2. Whether such IL-2 dependency is distinct from or in addition to an IL-7 requirement has been a confounding issue, particularly because...

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Detalhes bibliográficos
Main Authors: Kim, Grace Y., Ligons, Davinna L., Hong, Changwan, Luckey, Megan A., Keller, Hilary R., Tai, Xuguang, Lucas, Philip J., Gress, Ronald E., Park, Jung-Hyun
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370137/
https://ncbi.nlm.nih.gov/pubmed/22593613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102328
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