O-Fucose and Fringe-modified NOTCH1 extracellular domain fragments as decoys to release niche-lodged hematopoietic progenitor cells

Successful hematopoietic progenitor cell (HPC) transplant therapy is improved by mobilizing HPCs from the bone marrow niche in donors. Notch receptor–ligand interactions are known to retain HPCs in the bone marrow, and neutralizing antibodies against Notch ligands, Jagged-1 or Delta-like ligand (DLL...

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Dades bibliogràfiques
Publicat a:Glycobiology
Autors principals: Yu, Shuiliang, Wang, Weihuan, Albakri, Marwah, Yu, Xiaoxing, Majihail, Gurnoor, Lim, Seunghwan, Lopilato, Rachel K, Ito, Atsuko, Letterio, John, Haltiwanger, Robert S, Zhou, Lan
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2020
Matèries:
Cell Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8176772/
https://ncbi.nlm.nih.gov/pubmed/33351914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cwaa113
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