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O-Fucose and Fringe-modified NOTCH1 extracellular domain fragments as decoys to release niche-lodged hematopoietic progenitor cells

Successful hematopoietic progenitor cell (HPC) transplant therapy is improved by mobilizing HPCs from the bone marrow niche in donors. Notch receptor–ligand interactions are known to retain HPCs in the bone marrow, and neutralizing antibodies against Notch ligands, Jagged-1 or Delta-like ligand (DLL...

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Detalhes bibliográficos
Publicado no:Glycobiology
Main Authors: Yu, Shuiliang, Wang, Weihuan, Albakri, Marwah, Yu, Xiaoxing, Majihail, Gurnoor, Lim, Seunghwan, Lopilato, Rachel K, Ito, Atsuko, Letterio, John, Haltiwanger, Robert S, Zhou, Lan
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8176772/
https://ncbi.nlm.nih.gov/pubmed/33351914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cwaa113
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