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AC2P20 selectively kills Mycobacterium tuberculosis at acidic pH by depleting free thiols

Mycobacterium tuberculosis (Mtb) senses and adapts to host immune cues as part of its pathogenesis. One environmental cue sensed by Mtb is the acidic pH of its host niche in the macrophage phagosome. Disrupting the ability of Mtb to sense and adapt to acidic pH has the potential to reduce survival o...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:RSC Adv
Egile Nagusiak: Dechow, Shelby J., Coulson, Garry B., Wilson, Michael W., Larsen, Scott D., Abramovitch, Robert B.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Royal Society of Chemistry 2021
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8176622/
https://ncbi.nlm.nih.gov/pubmed/34168865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d1ra03181c
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