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AC2P20 selectively kills Mycobacterium tuberculosis at acidic pH by depleting free thiols
Mycobacterium tuberculosis (Mtb) senses and adapts to host immune cues as part of its pathogenesis. One environmental cue sensed by Mtb is the acidic pH of its host niche in the macrophage phagosome. Disrupting the ability of Mtb to sense and adapt to acidic pH has the potential to reduce survival o...
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| Publicado en: | RSC Adv |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The Royal Society of Chemistry
2021
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8176622/ https://ncbi.nlm.nih.gov/pubmed/34168865 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d1ra03181c |
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