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Leveraging eQTLs to identify individual-level tissue of interest for a complex trait
Genetic predisposition for complex traits often acts through multiple tissues at different time points during development. As a simple example, the genetic predisposition for obesity could be manifested either through inherited variants that control metabolism through regulation of genes expressed i...
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| Опубликовано в: : | PLoS Comput Biol |
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| Главные авторы: | , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2021
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8174686/ https://ncbi.nlm.nih.gov/pubmed/34019542 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008915 |
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