Optimized design of single-cell RNA sequencing experiments for cell-type-specific eQTL analysis

Single-cell RNA-sequencing (scRNA-Seq) is a compelling approach to directly and simultaneously measure cellular composition and state, which can otherwise only be estimated by applying deconvolution methods to bulk RNA-Seq estimates. However, it has not yet become a widely used tool in population-sc...

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Pubblicato in:Nat Commun
Autori principali: Mandric, Igor, Schwarz, Tommer, Majumdar, Arunabha, Hou, Kangcheng, Briscoe, Leah, Perez, Richard, Subramaniam, Meena, Hafemeister, Christoph, Satija, Rahul, Ye, Chun Jimmie, Pasaniuc, Bogdan, Halperin, Eran
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7599215/
https://ncbi.nlm.nih.gov/pubmed/33127880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19365-w
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