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Leveraging eQTLs to identify individual-level tissue of interest for a complex trait

Genetic predisposition for complex traits often acts through multiple tissues at different time points during development. As a simple example, the genetic predisposition for obesity could be manifested either through inherited variants that control metabolism through regulation of genes expressed i...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS Comput Biol
Prif Awduron: Majumdar, Arunabha, Giambartolomei, Claudia, Cai, Na, Haldar, Tanushree, Schwarz, Tommer, Gandal, Michael, Flint, Jonathan, Pasaniuc, Bogdan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2021
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8174686/
https://ncbi.nlm.nih.gov/pubmed/34019542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008915
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