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Leveraging input and output structures for joint mapping of epistatic and marginal eQTLs

Motivation: As many complex disease and expression phenotypes are the outcome of intricate perturbation of molecular networks underlying gene regulation resulted from interdependent genome variations, association mapping of causal QTLs or expression quantitative trait loci must consider both additiv...

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Detalhes bibliográficos
Main Authors: Lee, Seunghak, Xing, Eric P.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3371859/
https://ncbi.nlm.nih.gov/pubmed/22689753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bts227
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