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Sirtuin 3 Alleviates Diabetic Cardiomyopathy by Regulating TIGAR and Cardiomyocyte Metabolism

BACKGROUND: Impairment of glycolytic metabolism is suggested to contribute to diabetic cardiomyopathy. In this study, we explored the roles of SIRT3 (Sirtuin 3) on cardiomyocyte glucose metabolism and cardiac function. METHODS AND RESULTS: Exposure of H9c2 cardiomyocyte cell lines to high glucose (H...

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Podrobná bibliografie
Vydáno v:J Am Heart Assoc
Hlavní autoři: Li, Lanfang, Zeng, Heng, He, Xiaochen, Chen, Jian‐Xiong
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8174281/
https://ncbi.nlm.nih.gov/pubmed/33586458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.120.018913
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