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Sirtuin 3 Alleviates Diabetic Cardiomyopathy by Regulating TIGAR and Cardiomyocyte Metabolism

BACKGROUND: Impairment of glycolytic metabolism is suggested to contribute to diabetic cardiomyopathy. In this study, we explored the roles of SIRT3 (Sirtuin 3) on cardiomyocyte glucose metabolism and cardiac function. METHODS AND RESULTS: Exposure of H9c2 cardiomyocyte cell lines to high glucose (H...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Li, Lanfang, Zeng, Heng, He, Xiaochen, Chen, Jian‐Xiong
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8174281/
https://ncbi.nlm.nih.gov/pubmed/33586458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.120.018913
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