Group III phospholipase A2 downregulation attenuated survival and metastasis in ovarian cancer and promotes chemo-sensitization

BACKGROUND: Aberrant lipogenicity and deregulated autophagy are common in most advanced human cancer and therapeutic strategies to exploit these pathways are currently under consideration. Group III Phospholipase A2 (sPLA2-III/PLA2G3), an atypical secretory PLA2, is recognized as a regulator of lipi...

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Gepubliceerd in:J Exp Clin Cancer Res
Hoofdauteurs: Ray, Upasana, Roy, Debarshi, Jin, Ling, Thirusangu, Prabhu, Staub, Julie, Xiao, Yinan, Kalogera, Eleftheria, Wahner Hendrickson, Andrea E., Cullen, Grace D., Goergen, Krista, Oberg, Ann L., Shridhar, Viji
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2021
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Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8173968/
https://ncbi.nlm.nih.gov/pubmed/34082797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-021-01985-9
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