Quinacrine promotes autophagic cell death and chemosensitivity in ovarian cancer and attenuates tumor growth

A promising new strategy for cancer therapy is to target the autophagic pathway. In the current study, we demonstrate that the antimalarial drug Quinacrine (QC) reduces cell viability and promotes chemotherapy-induced cell death in an autophagy-dependent manner more extensively in chemoresistant cel...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Khurana, Ashwani, Roy, Debarshi, Kalogera, Eleftheria, Mondal, Susmita, Wen, Xuyang, He, Xiaoping, Dowdy, Sean, Shridhar, Viji
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742182/
https://ncbi.nlm.nih.gov/pubmed/26497553
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