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Loss of HSulf-1: The Missing Link between Autophagy and Lipid Droplets in Ovarian Cancer

Defective autophagy and deranged metabolic pathways are common in cancer; pharmacologic targeting of these two pathways could provide a viable therapeutic option. However, how these pathways are regulated by limited availability of growth factors is still unknown. Our study shows that HSulf-1 (endos...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Roy, Debarshi, Mondal, Susmita, Khurana, Ashwani, Jung, Deok-Beom, Hoffmann, Robert, He, Xiaoping, Kalogera, Eleftheria, Dierks, Thomas, Hammond, Edward, Dredge, Keith, Shridhar, Viji
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5294412/
https://ncbi.nlm.nih.gov/pubmed/28169314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep41977
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