Immune checkpoint inhibitor combination therapies very frequently induce secondary adrenal insufficiency

Immune checkpoint inhibitors (ICIs) are potent therapeutic options for many types of advanced cancer. The expansion of ICIs use however has led to an increase in immune-related adverse events (irAEs). Secondary adrenal insufficiency (AI) can be life-threatening especially in patients with delayed di...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Manaka, Katsunori, Sato, Junichiro, Takeuchi, Maki, Watanabe, Kousuke, Kage, Hidenori, Kawai, Taketo, Sato, Yusuke, Miyagawa, Takuya, Yamada, Daisuke, Kume, Haruki, Sato, Shinichi, Nagase, Takahide, Iiri, Taroh, Nangaku, Masaomi, Makita, Noriko
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8172846/
https://ncbi.nlm.nih.gov/pubmed/34078988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-91032-6
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