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Structures of human O-GlcNAcase and its complexes reveal a new substrate recognition mode
Human O-GlcNAcase (hOGA) is the unique enzyme responsible for the hydrolysis of the O-linked β-N-acetyl glucosamine (O-GlcNAc) modification, an essential protein glycosylation event that modulates the function of numerous cellular proteins in response to nutrients and stress. Here we report crystal...
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| Published in: | Nat Struct Mol Biol |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2017
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8171356/ https://ncbi.nlm.nih.gov/pubmed/28319083 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3390 |
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