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Structural insights into the substrate binding adaptability and specificity of human O-GlcNAcase
The O-linked β-N-acetyl glucosamine (O-GlcNAc) modification dynamically regulates the functions of numerous proteins. A single human enzyme O-linked β-N-acetyl glucosaminase (O-GlcNAcase or OGA) hydrolyzes this modification. To date, it remains largely unknown how OGA recognizes various substrates....
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| Publicado no: | Nat Commun |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5610315/ https://ncbi.nlm.nih.gov/pubmed/28939839 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00865-1 |
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