Intratumoral expression of interleukin 23 variants using oncolytic vaccinia virus elicit potent antitumor effects on multiple tumor models via tumor microenvironment modulation

Background: Newly emerging cancer immunotherapy has led to significant progress in cancer treatment; however, its efficacy is limited in solid tumors since the majority of them are “cold” tumors. Oncolytic viruses, especially when properly armed, can directly target tumor cells and indirectly modula...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Theranostics
Prif Awduron: Chen, Lingjuan, Chen, Hongqi, Ye, Junjie, Ge, Yan, Wang, Haiyan, Dai, Enyong, Ren, Jinghua, Liu, Weilin, Ma, Congrong, Ju, Songguang, Guo, Z. Sheng, Liu, Zuqiang, Bartlett, David L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Ivyspring International Publisher 2021
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8171085/
https://ncbi.nlm.nih.gov/pubmed/34093846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.56494
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