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In Situ Therapeutic Cancer Vaccination with an Oncolytic Virus Expressing Membrane-Tethered IL-2

Successful in situ therapeutic vaccination would allow locally delivered oncolytic virus (OV) to exert systemic immunologic effects on metastases and improve survival. We have utilized bilateral flank tumor models to determine the most efficacious regimens of in situ vaccination. Intratumoral inject...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Ther Oncolytics
Prif Awduron: Liu, Weilin, Dai, Enyong, Liu, Zuqiang, Ma, Congrong, Guo, Zong Sheng, Bartlett, David L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society of Gene & Cell Therapy 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7210382/
https://ncbi.nlm.nih.gov/pubmed/32405533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omto.2020.04.006
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