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In Situ Therapeutic Cancer Vaccination with an Oncolytic Virus Expressing Membrane-Tethered IL-2

Successful in situ therapeutic vaccination would allow locally delivered oncolytic virus (OV) to exert systemic immunologic effects on metastases and improve survival. We have utilized bilateral flank tumor models to determine the most efficacious regimens of in situ vaccination. Intratumoral inject...

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Detalhes bibliográficos
Publicado no:Mol Ther Oncolytics
Main Authors: Liu, Weilin, Dai, Enyong, Liu, Zuqiang, Ma, Congrong, Guo, Zong Sheng, Bartlett, David L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7210382/
https://ncbi.nlm.nih.gov/pubmed/32405533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omto.2020.04.006
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