Discovery of a cooperative mode of inhibiting RIPK1 kinase

RIPK1, a death domain-containing kinase, has been recognized as an important therapeutic target for inhibiting apoptosis, necroptosis, and inflammation under pathological conditions. RIPK1 kinase inhibitors have been advanced into clinical studies for the treatment of various human diseases. One of...

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Bibliografski detalji
Izdano u:Cell Discov
Glavni autori: Meng, Huyan, Wu, Guowei, Zhao, Xinsuo, Wang, Anhui, Li, Dekang, Tong, Yilun, Jin, Taijie, Cao, Ye, Shan, Bing, Hu, Shichen, Li, Ying, Pan, Lifeng, Tian, Xiaoxu, Wu, Ping, Peng, Chao, Yuan, Junying, Li, Guohui, Tan, Li, Wang, Zhaoyin
Format: Artigo
Jezik:Inglês
Izdano: Springer Singapore 2021
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8169668/
https://ncbi.nlm.nih.gov/pubmed/34075030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41421-021-00278-x
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