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Progressive parkinsonism due to mitochondrial impairment: lessons from the MitoPark mouse model

The cardinal pathophysiological finding of Parkinson’s disease (PD) is a chronic, progressive degeneration of dopamine (DA) neurons in the substantia nigra, which is responsible for the motor and some of the non-motor symptomatology. While the primary causes of nigrostriatal degeneration are hotly d...

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Bibliografiske detaljer
Udgivet i:Exp Neurol
Main Authors: Beckstead, Michael J., Howell, Rebecca D.
Format: Artigo
Sprog:Inglês
Udgivet: 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8169575/
https://ncbi.nlm.nih.gov/pubmed/33753138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2021.113707
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