Cell-surface antigen profiling of pediatric brain tumors: B7-H3 is consistently expressed and can be targeted via local or systemic CAR T-cell delivery

BACKGROUND: Immunotherapy with chimeric antigen receptor (CAR) T cells is actively being explored for pediatric brain tumors in preclinical models and early phase clinical studies. At present, it is unclear which CAR target antigens are consistently expressed across different pediatric brain tumor t...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Neuro Oncol
Hlavní autoři: Haydar, Dalia, Houke, Haley, Chiang, Jason, Yi, Zhongzhen, Odé, Zelda, Caldwell, Kenneth, Zhu, Xiaoyan, Mercer, Kimberly S, Stripay, Jennifer L, Shaw, Timothy I, Vogel, Peter, DeRenzo, Christopher, Baker, Suzanne J, Roussel, Martine F, Gottschalk, Stephen, Krenciute, Giedre
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2020
Témata:
Basic and Translational Investigations
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8168826/
https://ncbi.nlm.nih.gov/pubmed/33320196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa278
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky