Cell-surface antigen profiling of pediatric brain tumors: B7-H3 is consistently expressed and can be targeted via local or systemic CAR T-cell delivery

BACKGROUND: Immunotherapy with chimeric antigen receptor (CAR) T cells is actively being explored for pediatric brain tumors in preclinical models and early phase clinical studies. At present, it is unclear which CAR target antigens are consistently expressed across different pediatric brain tumor t...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Neuro Oncol
Main Authors: Haydar, Dalia, Houke, Haley, Chiang, Jason, Yi, Zhongzhen, Odé, Zelda, Caldwell, Kenneth, Zhu, Xiaoyan, Mercer, Kimberly S, Stripay, Jennifer L, Shaw, Timothy I, Vogel, Peter, DeRenzo, Christopher, Baker, Suzanne J, Roussel, Martine F, Gottschalk, Stephen, Krenciute, Giedre
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2020
Assuntos:
Basic and Translational Investigations
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8168826/
https://ncbi.nlm.nih.gov/pubmed/33320196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa278
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares