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High fructose drives the serine synthesis pathway in acute myeloid leukemic cells

A significant increase in dietary fructose consumption has been implicated as a potential driver of cancer. Metabolic adaptation of cancer cells to utilize fructose confers advantages for their malignant growth, but compelling therapeutic targets have not been identified. Here, we show that fructose...

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Detalhes bibliográficos
Publicado no:Cell Metab
Principais autores: Jeong, Sangmoo, Savino, Angela Maria, Chirayil, Rachel, Barin, Ersilia, Cheng, Yuanming, Park, Sun-Mi, Schurer, Alexandra, Mullarky, Edouard, Cantley, Lewis C., Kharas, Michael G., Keshari, Kayvan R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8168776/
https://ncbi.nlm.nih.gov/pubmed/33357456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2020.12.005
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