Lipid signalling enforces T(reg) cell functional specialization in tumours

Regulatory T (T(reg)) cells are essential for immune tolerance1 but also drive immunosuppression in the tumour microenvironment (TME)2. Therapeutic targeting of T(reg) cells in cancer requires the identification of context-specific mechanisms for T(reg) cell function. Here we demonstrate that inhibi...

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Udgivet i:Nature
Main Authors: Lim, Seon Ah, Wei, Jun, Nguyen, Thanh-Long M., Shi, Hao, Su, Wei, Palacios, Gustavo, Dhungana, Yogesh, Chapman, Nicole M., Long, Lingyun, Saravia, Jordy, Vogel, Peter, Chi, Hongbo
Format: Artigo
Sprog:Inglês
Udgivet: 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8168716/
https://ncbi.nlm.nih.gov/pubmed/33627871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-021-03235-6
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