Protein prenylation drives discrete signaling programs for the differentiation and maintenance of effector T(reg) cells

Effector regulatory T (eT(reg)) cells are essential for immune tolerance and depend upon T cell receptor (TCR) signals for generation. The immunometabolic signaling mechanisms that promote the differentiation and maintenance of eT(reg) cells remain unclear. Here, we show that isoprenoid-dependent po...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Metab
Prif Awduron: Su, Wei, Chapman, Nicole M., Wei, Jun, Zeng, Hu, Dhungana, Yogesh, Shi, Hao, Saravia, Jordy, Zhou, Peipei, Long, Lingyun, Rankin, Sherri, Anil, KC, Vogel, Peter, Chi, Hongbo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2020
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7887758/
https://ncbi.nlm.nih.gov/pubmed/33207246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2020.10.022
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