EPCT-23 PRE-CLINICAL STUDY OF FOCUSED ULTRASOUND-MEDIATED BLOOD-BRAIN BARRIER OPENING AND PANOBINOSTAT FOR DIFFUSE INTRINSIC PONTINE GLIOMA TREATMENT

Diffuse intrinsic pontine glioma (DIPG) is the lethal high-grade brain tumor in children with no effective treatment options to date. Despite excessive clinical trials, the prognosis remains poor, with a median overall survival (mOS) of less than 1 year. Genomic studies of DIPG tissue have identifie...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Wei, Hong-Jian, Pouliopoulos, Antonios, Yoh, Nina, Tazhibi, Masih, McQuillan, Nicholas, Zhang, Xu, Szalontay, Luca, Gartrell, Robyn, Pavisic, Jovana, Zhang, Zhiguo, Feldstein, Neil, Becher, Oren, Zacharoulis, Stergios, Konofagou, Elisa, Wu, Cheng-Chia
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
Assuntos:
Translational/Early Phase Clinical Trials
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8168249/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noab090.209
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