LGG-09. SENOLYTIC AGENT NAVITOCLAX TARGETS VINBLASTINE- AND MAPK INHIBITORS-INDUCED SENESCENT TUMOUR CELLS IN PAEDIATRIC LOW GRADE GLIOMAS

Pilocytic astrocytoma (PA, WHO grade I), the most common paediatric brain tumour, is characterized by constitutive activation of the MAPK pathway. PA tumours show a slow growth, without tendency to progress to high-grade malignancies. However, a significant group of patients for whom a total resecti...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Neuro Oncol
Egile Nagusiak: Guiho, Romain, Selt, Florian, Stone, Thomas, Jacques, Thomas, Hargrave, Darren, Gil, Jesús, Witt, Olaf, Milde, Till, Barbera, Juan Pedro Martinez
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2021
Gaiak:
Low Grade Gliomas
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8168216/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noab090.133
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