RARE-02. POLYAMINE PATHWAY INHIBITION IS A POTENT NOVEL THERAPEUTIC STRATEGY AGAINST DIFFUSE INTRINSIC PONTINE GLIOMA

Diffuse intrinsic pontine glioma (DIPG) is an aggressive paediatric brainstem tumour, with a median survival of less than 1 year. Polyamines are intracellular polycations that control important aspects of cell growth and are often upregulated in cancer. Difluoromethylornithine (DFMO) is an FDA-appro...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Khan, Aaminah, Gamble, Laura, Upton, Dannielle, Yu, Denise, Pandher, Ruby, Mayoh, Chelsea, Burns, Mark R, Norris, Murray D, Haber, Michelle, Tsoli, Maria, Ziegler, David S
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
Assuntos:
Rare Tumors/Other
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8168151/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noab090.163
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados