DIPG-01. TARGETING THE POLYAMINE PATHWAY AS A NOVEL THERAPEUTIC TREATMENT AGAINST DIFFUSE INTRINSIC PONTINE GLIOMA

Diffuse intrinsic pontine glioma (DIPG) is an aggressive paediatric brainstem tumour, with a median survival below 1 year. Polyamines, frequently upregulated in cancer, are small intracellular polycations that control key biological processes including cell replication, translation and differentiati...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Khan, Aaminah, Gamble, Laura, Yu, Denise, Joshi, Swapna, Franshaw, Laura, Burns, Mark, Norris, Murray, Haber, Michelle, Tsoli, Maria, Ziegler, David
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012726/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.095
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