Upregulation of endogenous TRAIL-elicited apoptosis is essential for metformin-mediated antitumor activity against TNBC and NSCLC

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) shows promising antitumor activity in preclinical studies. However, the efficacy of recombinant TRAIL in clinical trials is compromised by its short serum half-life and low in vivo stability. Induction of endogenous TRAIL may overcome t...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Mol Ther Oncolytics
Main Authors: Liu, Shuang, Polsdofer, Erik V., Zhou, Lukun, Ruan, Sanbao, Lyu, Hui, Hou, Defu, Liu, Hao, Thor, Ann D., He, Zhimin, Liu, Bolin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2021
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8167201/
https://ncbi.nlm.nih.gov/pubmed/34141868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omto.2021.04.012
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados