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Understanding the biology of HER3 receptor as a therapeutic target in human cancer

HER3 belongs to the human epidermal growth factor receptor (HER) family which also includes HER1/EGFR/erbB1, HER2/erbB2, and HER4/erbB4. As a unique member of the HER family, HER3 lacks or has little intrinsic tyrosine kinase activity. It frequently co-expresses and forms heterodimers with other rec...

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Detalhes bibliográficos
Publicado no:Acta Pharm Sin B
Main Authors: Lyu, Hui, Han, Amy, Polsdofer, Erik, Liu, Shuang, Liu, Bolin
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6090011/
https://ncbi.nlm.nih.gov/pubmed/30109175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apsb.2018.05.010
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