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Targeting of HER3 with Functional Cooperative miRNAs Enhances Therapeutic Activity in HER2-Overexpressing Breast Cancer Cells

BACKGROUND: The HER3 receptor functions as a major cause of drug resistance in cancer treatment. It is believed that therapeutic targeting of HER3 is required to improve patient outcomes. It is not clear whether a novel strategy with two functional cooperative miRNAs would effectively inhibit erbB3...

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Detalhes bibliográficos
Publicado no:Biol Proced Online
Main Authors: Lyu, Hui, Huang, Jingcao, He, Zhimin, Liu, Bolin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6081814/
https://ncbi.nlm.nih.gov/pubmed/30093840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12575-018-0081-x
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