Upregulation of endogenous TRAIL-elicited apoptosis is essential for metformin-mediated antitumor activity against TNBC and NSCLC

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) shows promising antitumor activity in preclinical studies. However, the efficacy of recombinant TRAIL in clinical trials is compromised by its short serum half-life and low in vivo stability. Induction of endogenous TRAIL may overcome t...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Mol Ther Oncolytics
Päätekijät: Liu, Shuang, Polsdofer, Erik V., Zhou, Lukun, Ruan, Sanbao, Lyu, Hui, Hou, Defu, Liu, Hao, Thor, Ann D., He, Zhimin, Liu, Bolin
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society of Gene & Cell Therapy 2021
Aiheet:
Original Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8167201/
https://ncbi.nlm.nih.gov/pubmed/34141868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omto.2021.04.012
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia