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Association of APOE Genotype With Heterogeneity of Cognitive Decline Rate in Alzheimer Disease

OBJECTIVE: To test the hypothesis that the APOE genotype is a significant driver of heterogeneity in Alzheimer disease (AD) clinical progression, which could have important implications for clinical trial design and interpretation. METHODS: We applied novel reverse-time longitudinal models to analyz...

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Detalhes bibliográficos
Publicado no:Neurology
Main Authors: Qian, Jing, Betensky, Rebecca A., Hyman, Bradley T., Serrano-Pozo, Alberto
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8166439/
https://ncbi.nlm.nih.gov/pubmed/33771840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000011883
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