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Plaque-Associated Local Toxicity Increases over the Clinical Course of Alzheimer Disease

Amyloid (senile) plaques, one of the two pathologic hallmarks of Alzheimer disease (AD), are associated with dystrophic neurites and glial responses, both astrocytic and microglial. Although plaque burden remains relatively stable through the clinical course of AD, whether these features of local pl...

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Detalhes bibliográficos
Publicado no:Am J Pathol
Main Authors: Serrano-Pozo, Alberto, Betensky, Rebecca A., Frosch, Matthew P., Hyman, Bradley T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4729270/
https://ncbi.nlm.nih.gov/pubmed/26687817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2015.10.010
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