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Plaque-Associated Local Toxicity Increases over the Clinical Course of Alzheimer Disease

Amyloid (senile) plaques, one of the two pathologic hallmarks of Alzheimer disease (AD), are associated with dystrophic neurites and glial responses, both astrocytic and microglial. Although plaque burden remains relatively stable through the clinical course of AD, whether these features of local pl...

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Vydáno v:Am J Pathol
Hlavní autoři: Serrano-Pozo, Alberto, Betensky, Rebecca A., Frosch, Matthew P., Hyman, Bradley T.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4729270/
https://ncbi.nlm.nih.gov/pubmed/26687817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2015.10.010
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