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Stable Size Distribution of Amyloid Plaques Over the Course of Alzheimer Disease

Amyloid-β plaques are a key pathological feature of Alzheimer disease (AD), but whether plaque sizes increase or stabilize over the course of AD is unknown. We measured the size distribution of total immunoreactive (10D5-positive) and dense-core (Thioflavine-S-positive) plaques in the temporal neoco...

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Detalhes bibliográficos
Main Authors: Serrano-Pozo, Alberto, Mielke, Matthew L., Muzitansky, Alona, Gómez-Isla, Teresa, Growdon, John H., Bacskai, Brian J., Betensky, Rebecca A., Frosch, Matthew P., Hyman, Bradley T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3407299/
https://ncbi.nlm.nih.gov/pubmed/22805771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/NEN.0b013e31825e77de
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