Tolerance to nascent protein misfolding stress requires fine-tuning of the cAMP/PKA pathway

Protein aggregation is the abnormal association of misfolded proteins into larger, often insoluble structures that can be toxic during aging and in protein aggregation-associated diseases. Previous research has established a role for the cytosolic Tsa1 peroxiredoxin in responding to protein misfoldi...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Kritsiligkou, Paraskevi, Nowicki-Osuch, Karol, Carter, Zorana, Kershaw, Chris J., Creamer, Declan R., Weids, Alan J., Grant, Chris M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8164027/
https://ncbi.nlm.nih.gov/pubmed/33894203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100690
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