FXR-Deoxycholic Acid-TNF-α Axis Modulates Acetaminophen-Induced Hepatotoxicity

The idiosyncratic characteristics and severity of acetaminophen (APAP) overdose-induced hepatotoxicity render identifying the predisposing factors and mechanisms of APAP-induced liver toxicity necessary and urgent. Farnesoid X receptor (FXR) controls bile acid homeostasis and modulates the progressi...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Toxicol Sci
Hlavní autoři: Yan, Tingting, Yan, Nana, Wang, Hong, Yagai, Tomoki, Luo, Yuhong, Takahashi, Shogo, Zhao, Min, Krausz, Kristopher W, Wang, Guangji, Hao, Haiping, Gonzalez, Frank J
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2021
Témata:
Molecular, Biochemical, and Systems Toxicology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8163055/
https://ncbi.nlm.nih.gov/pubmed/33662127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfab027
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky