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Mitochondrial–Lysosomal Axis in Acetaminophen Hepatotoxicity

Acetaminophen (APAP) toxicity is the most common cause of acute liver failure and a major indication for liver transplantion in the United States and Europe. Although significant progress has been made in understanding the molecular mechanisms underlying APAP hepatotoxicity, there is still an urgent...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Moles, Anna, Torres, Sandra, Baulies, Anna, Garcia-Ruiz, Carmen, Fernandez-Checa, Jose C.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5968389/
https://ncbi.nlm.nih.gov/pubmed/29867464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00453
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