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Macrocyclization of bis-indole quinolines for selective stabilization of G-quadruplex DNA structures
The recognition of G-quadruplex (G4) DNA structures as important regulatory elements in biological mechanisms, and the connection between G4s and the evolvement of different diseases, has sparked interest in developing small organic molecules targeting G4s. However, such compounds often lack drug-li...
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| Udgivet i: | Chem Sci |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Royal Society of Chemistry
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8162405/ https://ncbi.nlm.nih.gov/pubmed/34094311 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0sc03519j |
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