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Subtle structural alterations in G-quadruplex DNA regulate site specificity of fluorescence light-up probes

G-quadruplex (G4) DNA structures are linked to key biological processes and human diseases. Small molecules that target specific G4 DNA structures and signal their presence would therefore be of great value as chemical research tools with potential to further advance towards diagnostic and therapeut...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Principais autores: Kumar, Rajendra, Chand, Karam, Bhowmik, Sudipta, Das, Rabindra Nath, Bhattacharjee, Snehasish, Hedenström, Mattias, Chorell, Erik
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7026600/
https://ncbi.nlm.nih.gov/pubmed/31912160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz1205
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