The Timing and Abundance of IL-2Rβ (CD122) Expression Control Thymic iNKT Cell Generation and NKT1 Subset Differentiation

Invariant NKT (iNKT) cells are thymus-generated innate-like T cells, comprised of three distinct subsets with divergent effector functions. The molecular mechanism that drives the lineage trifurcation of immature iNKT cells into the NKT1, NKT2, and NKT17 subsets remains a controversial issue that re...

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Dades bibliogràfiques
Publicat a:Front Immunol
Autors principals: Won, Hee Yeun, Kim, Hye Kyung, Crossman, Assiatu, Awasthi, Parirokh, Gress, Ronald E., Park, Jung-Hyun
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2021
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8161506/
https://ncbi.nlm.nih.gov/pubmed/34054809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.642856
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