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Myeloid cells activate iNKT cells to produce IL-4 in the thymic medulla
Interleukin-4 (IL-4) is produced by a unique subset of invariant natural killer T (iNKT) cells (NKT2) in the thymus in the steady state, where it conditions CD8(+) T cells to become “memory-like” among other effects. However, the signals that cause NKT2 cells to constitutively produce IL-4 remain po...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6825307/ https://ncbi.nlm.nih.gov/pubmed/31611396 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1910412116 |
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